Auto Pure Type 1 Water Purification System

Get your free water needs cost analysis and save 50% or more on your lab’s ultrapure water expenses.

What do you need a lab water purification system for?

  • Setting up a new lab?
  • Upgrading your HPLC or other analytical system?
  • Performing experiments in an EDU setting?
  • Running high-throughput analyses in the life sciences?
  • DNA sequencing, PCR, or cell culture work?

Everything you do that uses 18.2 MΩ.cm. water costs money. The managers and executive who worry about the money need to control costs. You can help them (and preserve your job by doing it).

Yamato lab water purification systems are the lowest cost of ownership and the lowest cost per liter of ultrapure water available to your lab.

Choose your model below and wash away budget waste.

Uncover the secret nobody else in your lab knows

Ultrapure water from Brand B is the exact same as ultrapure water from Brand Y (that’s us).

Both integrate with your application in the exact same way.

But everybody always seems to talk about Brand B – and Brand B has a total cost of ownership that’s as much as 3X higher than Brand Y.

Plus Brand B’s filter cartridges are a huge cost for your lab.

So if you’re not sure what you need, but you know your lab is interested in controlling costs, contact us for a water needs cost analysis and let us do the work of figuring it out.

Contact us for your free water needs cost analysis

Get larger filters at ⅓ the cost

Your replacement filter cartridges from Yamato are almost 2X as large (and ⅓ the price) of the nearest competitor.

They’re 3X larger than the industry’s leading brand, and deliver the same quality of water with an equal or better flow rate to your HLPC, LCMS, ICP-MS, AAS, or other instrument.

*based on 3rd party testing vs 4 leading brands (2021)

Make new labs profitable faster, and control your costs for the next decade

The cost of ownership of our new Yamato Auto Pure filters after 4 months looks to be about 55% lower than our previous Barnstead filters. We’ve moved 5 of our large systems over to Yamato as a test, and we’ll be moving the rest over at the start of next quarter.

Gurdeep Singh, Lab Director

We’re expanding the lab and invested in 3 Yamato water purifiers. In our analysis, it was one of the easiest ways to make the new lab more viable and recover our investment in a more timely way.

Chris Forbes, Director

The executive team is keeping a close eye on profits in the lab. This is one of the ways we cut costs and increase those profits, and it had an immediate and measurable effect on the lab’s budget.

Evangeline Dewar, Lab Manager

Lab water purification FAQs

Q: What is reagent grade water?

A: Technically, reagent grade water is any water used for your analytical process. Lab quality water that achieves a standard that does not influence your process, method, or application.

Reagent grade water, depending on your application, can be anywhere from Type 1 ultrapure water to semipure type 4 water.

  • Type 1 ultrapure water has resistivity of > 18 MΩ-cm, conductivity of < 0.056 µS/cm, and < 50 ppb TOC. This quality of reagent water is used for critical applications like HPLC, GC, mammalian cell culture and IVF, mass spectrometry, reagents for molecular biology applications, such as PCR and DNA sequencing, and preparation of solutions for electrophoresis and blotting.
  • Type 2 lab water has resistivity of > 1 MΩ-cm, conductivity is < 1 µS/cm, and TOCs are < 50 ppb. Your lab uses it in cell culture incubators, to feed instruments and analyzers, to make buffers, pH solutions, microbiological culture preparation, or as feed water to a Type 1 system to reduce calcium build-up.
  • Type 3 water has resistivity of > 4 MΩ-cm, conductivity of < 0.25 µS/cm, and < 200 ppb of TOCs. Most impurities are removed from Type 3 water via reverse osmosis of tap water. It’s used to rinse glassware, perform non-critical laboratory applications, and in instruments like autoclaves or heating baths. Like type 2 water, it’s used as feed water for ultrapure systems.
  • Type 4 semipure water has resistivity of 200KΩ and a conductivity of < 5µS/cm. It’s mostly used as feed water to other systems, reducing the burden on the more expensive filter cartridges so labs can control their costs more efficiently.

Q: What grade water do I need for HPLC?

A: Type 1 ultrapure water is required for multiple stages of HPLC.

  • Reagent prep.
  • Buffers
  • Mobile phases
  • Other sample pre-treatments.

Pairing HPLC or UHPLC with mass spectrometry for ultra-sensitive liquid chromatography-mass spectrometry applications additionally calls for water with very low levels of Total Organic Carbon (TOC). A low TOC value of < 5 ppb and bacteria levels below 0.1 CFU/ml is recommended.

Your system can be built around this Yamato Auto Pure WG series.

Q: What is the right reagent water for cell culture?

A: Type 1 ultrapure water is required for cell culture to limit the sample’s exposure to contaminants unrelated to the experiment.

The Auto Pure WB series is built for labs doing cell culture. You can learn about it here.

Save 50% or more on the ultrapure water your lab makes

Don’t let brand loyalty dictate your budget.

Install 1 Yamato system and compare your expense over the next quarter to your other systems. When you see the savings, we’ll help you find the appropriate models to replace those water purification cost centers in your lab.

Contact us here and we’ll answer your questions today

Lab Water Purification Systems

Solutions are sensitive to contaminants, so any imbalance in the mixture invalidates the results of your experiment. Impure water contains contaminants that pose risks. As a result, water should undergo a purification process to reach a certain level of purity. Our lab water purification systems here at Yamato can help you produce ASTM Type 1, Type 2, and Type 3 water quality. Besides that, our lab water purification systems can help you with the following applications:

Buffers and reagents

A buffer corrects the pH level of any solution. On the other hand, a reagent stimulates a reaction to detect the absence or presence of other substances. Both solutions are prepared by dissolving solid reagents in pure water that are free from any substances that affect the acidity or pH level of the solutions.

Since water is a major solvent involved in creating these solutions, a deionized water system for laboratories is necessary to produce water with high levels of purity. The Yamato Auto Pure WA300 series water purification systems can remove dissolved minerals through high-purity ion exchange resins to process high-quality pure water, which is ideal for preparing both solutions.

Cell culture

Normal water contains compounds that affect cell culture which includes bacteria, endotoxin, organic ions, and organic compounds. These contaminants can cause chemical reactions, changes in pH levels, and disrupt or kill various cells.

Moreover, water is also used in producing buffers and rinsing bioreactors and other materials. Therefore, producing laboratory grade water is necessary. This is usually achieved using Yamato Auto Pure WB300 series water purification systems. These units are great in removing bacteria and particulates to reach type 1 water quality, the highest level of purity in water.

Reverse osmosis

In order to make Type 1 or Type 2 water, feed water quality is important. Reverse osmosis is used as pretreatment of raw water just before feeding it to water purifiers which can produce Type1 or Type 2 water.


Traditional method of producing purified water is distillation, which is the process of separating liquid mixtures through condensation. Academia and certain applications require the heat treated distilled water. Yamato Auto Still series water purifiers can produce distilled water.